Effect of Steric Constraint at the γ-Backbone Position on the Conformations and Hybridization Properties of PNAs

Conformationally preorganized peptide nucleic acids (PNAs) have been synthesized through backbone modifications at the γ-position, where R = alanine, valine, isoleucine, and phenylalanine side chains. The effects of these side-chains on the conformations and hybridization properties of PNAs were det...

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Autores principales: Crawford, Matthew J., Rapireddy, Srinivas, Bahal, Raman, Sacui, Iulia, Ly, Danith H.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3138043/
https://ncbi.nlm.nih.gov/pubmed/21776375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/652702
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