Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development
Pax6 is a key transcription factor in eye development, particularly in lens development, but its molecular action has not been clarified. We demonstrate that Pax6 initiates lens development by forming a molecular complex with SOX2 on the lens-specific enhancer elements, e.g., the δ-crystallin minima...
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| 出版年: | Genes Dev |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2001
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11358870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.887101 |
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