Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development

Pax6 is a key transcription factor in eye development, particularly in lens development, but its molecular action has not been clarified. We demonstrate that Pax6 initiates lens development by forming a molecular complex with SOX2 on the lens-specific enhancer elements, e.g., the δ-crystallin minima...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Kamachi, Yusuke, Uchikawa, Masanori, Tanouchi, Aki, Sekido, Ryohei, Kondoh, Hisato
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2001
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313803/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11358870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.887101
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