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Pax6 and SOX2 form a co-DNA-binding partner complex that regulates initiation of lens development
Pax6 is a key transcription factor in eye development, particularly in lens development, but its molecular action has not been clarified. We demonstrate that Pax6 initiates lens development by forming a molecular complex with SOX2 on the lens-specific enhancer elements, e.g., the δ-crystallin minima...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC313803/ https://ncbi.nlm.nih.gov/pubmed/11358870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.887101 |
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