Functional Dissection of the Oct6 Schwann Cell Enhancer Reveals an Essential Role for Dimeric Sox10 Binding

The POU domain transcription factor Pou3f1 (Oct6/Scip/Tst1) initiates the transition from ensheathing, promyelinating Schwann cells to myelinating cells. Axonal and other extracellular signals regulate Oct6 expression through the Oct6 Schwann cell enhancer (SCE), which is both required and sufficien...

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Hlavní autoři: Jagalur, Noorjahan B., Ghazvini, Mehrnaz, Mandemakers, Wim, Driegen, Siska, Maas, Alex, Jones, Erin A., Jaegle, Martine, Grosveld, Frank, Svaren, John, Meijer, Dies
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137940/
https://ncbi.nlm.nih.gov/pubmed/21653862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0659-11.2011
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