Functional Dissection of the Oct6 Schwann Cell Enhancer Reveals an Essential Role for Dimeric Sox10 Binding

The POU domain transcription factor Pou3f1 (Oct6/Scip/Tst1) initiates the transition from ensheathing, promyelinating Schwann cells to myelinating cells. Axonal and other extracellular signals regulate Oct6 expression through the Oct6 Schwann cell enhancer (SCE), which is both required and sufficien...

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Main Authors: Jagalur, Noorjahan B., Ghazvini, Mehrnaz, Mandemakers, Wim, Driegen, Siska, Maas, Alex, Jones, Erin A., Jaegle, Martine, Grosveld, Frank, Svaren, John, Meijer, Dies
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137940/
https://ncbi.nlm.nih.gov/pubmed/21653862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0659-11.2011
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