Functional Dissection of the Oct6 Schwann Cell Enhancer Reveals an Essential Role for Dimeric Sox10 Binding

The POU domain transcription factor Pou3f1 (Oct6/Scip/Tst1) initiates the transition from ensheathing, promyelinating Schwann cells to myelinating cells. Axonal and other extracellular signals regulate Oct6 expression through the Oct6 Schwann cell enhancer (SCE), which is both required and sufficien...

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Bibliografiska uppgifter
Huvudupphovsmän: Jagalur, Noorjahan B., Ghazvini, Mehrnaz, Mandemakers, Wim, Driegen, Siska, Maas, Alex, Jones, Erin A., Jaegle, Martine, Grosveld, Frank, Svaren, John, Meijer, Dies
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2011
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137940/
https://ncbi.nlm.nih.gov/pubmed/21653862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0659-11.2011
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