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Does Anesthetic Additivity Imply a Similar Molecular Mechanism of Anesthetic Action at N-Methyl-d-Aspartate Receptors?

BACKGROUND: Isoflurane and carbon dioxide (CO(2)) negatively modulate N-methyl-D-aspartate (NMDA) receptors, but via different mechanisms. Isoflurane is a competitive antagonist at the NMDA receptor glycine binding site, whereas CO(2) inhibits NMDA receptor current through extracellular acidificatio...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Brosnan, Robert J., Pham, Trung L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137916/
https://ncbi.nlm.nih.gov/pubmed/21233494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/ANE.0b013e3182080599
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