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The hedgehog/Gli signaling paradigm in prostate cancer
Hedgehog is a ligand-activated signaling pathway that regulates Gli-mediated transcription. Although most noted for its role as an embryonic morphogen, hyperactive hedgehog also causes human skin and brain malignancies. The hedgehog-related gene anomalies found in these tumors are rarely found in pr...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137913/ https://ncbi.nlm.nih.gov/pubmed/21776292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/EEM.11.2 |
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