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The hedgehog/Gli signaling paradigm in prostate cancer

Hedgehog is a ligand-activated signaling pathway that regulates Gli-mediated transcription. Although most noted for its role as an embryonic morphogen, hyperactive hedgehog also causes human skin and brain malignancies. The hedgehog-related gene anomalies found in these tumors are rarely found in pr...

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Bibliografiska uppgifter
Huvudupphovsmän: Chen, Mengqian, Carkner, Richard, Buttyan, Ralph
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137913/
https://ncbi.nlm.nih.gov/pubmed/21776292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/EEM.11.2
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