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The Inflammatory Cytokines TWEAK and TNFα Reduce Renal Klotho Expression through NFκB
Proinflammatory cytokines contribute to renal injury, but the downstream effectors within kidney cells are not well understood. One candidate effector is Klotho, a protein expressed by renal cells that has antiaging properties; Klotho-deficient mice have an accelerated aging-like phenotype, includin...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Nephrology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137579/ https://ncbi.nlm.nih.gov/pubmed/21719790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010101073 |
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