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Photo-products of retinal pigment epithelial bisretinoids react with cellular thiols

PURPOSE: Bisretinoids such as A2E that accumulate as components of the lipofuscin of retinal pigment epithelial cells are implicated in some retinal disease processes. These compounds undergo light-induced oxidation and cleavage with the latter releasing of a mixture of aldehyde-bearing fragments, i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Yoon, Kee Dong, Yamamoto, Kazunori, Zhou, Jilin, Sparrow, Janet R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Molecular Vision 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137558/
https://ncbi.nlm.nih.gov/pubmed/21850158
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