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Photo-products of retinal pigment epithelial bisretinoids react with cellular thiols
PURPOSE: Bisretinoids such as A2E that accumulate as components of the lipofuscin of retinal pigment epithelial cells are implicated in some retinal disease processes. These compounds undergo light-induced oxidation and cleavage with the latter releasing of a mixture of aldehyde-bearing fragments, i...
Gardado en:
| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Molecular Vision
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137558/ https://ncbi.nlm.nih.gov/pubmed/21850158 |
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