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Genetic and Biochemical Evaluation of the Importance of Cdc6 in Regulating Mitotic Exit

We evaluated the hypothesis that the N-terminal region of the replication control protein Cdc6 acts as an inhibitor of cyclin-dependent kinase (Cdk) activity, promoting mitotic exit. Cdc6 accumulation is restricted to the period from mid-cell cycle until the succeeding G1, due to proteolytic control...

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Vydáno v:Mol Biol Cell
Hlavní autoři: Archambault, Vincent, Li, Caihong X., Tackett, Alan J., Wäsch, Ralph, Chait, Brian T., Rout, Michael P., Cross, Frederick R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Cell Biology 2003
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313736/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12960422/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E03-06-0384
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