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Genetic and Biochemical Evaluation of the Importance of Cdc6 in Regulating Mitotic Exit

We evaluated the hypothesis that the N-terminal region of the replication control protein Cdc6 acts as an inhibitor of cyclin-dependent kinase (Cdk) activity, promoting mitotic exit. Cdc6 accumulation is restricted to the period from mid-cell cycle until the succeeding G1, due to proteolytic control...

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Detalhes bibliográficos
Main Authors: Archambault, Vincent, Li, Caihong X., Tackett, Alan J., Wäsch, Ralph, Chait, Brian T., Rout, Michael P., Cross, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC313736/
https://ncbi.nlm.nih.gov/pubmed/12960422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-06-0384
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