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Screening for GPCR Ligands Using Surface Plasmon Resonance
[Image: see text] G-protein coupled receptors (GPCRs) are a class of drug targets of primary importance. However, receptor assays are based on measurement of either ligand displacement or downstream functional responses, rather than direct observation of ligand binding. Issues of allosteric modulati...
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| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Chemical Society
2011
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| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137231/ https://ncbi.nlm.nih.gov/pubmed/21765967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2000017 |
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