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Mammalian Target of Rapamycin Signaling and Autophagy: Roles in Lymphangioleiomyomatosis Therapy
The pace of progress in lymphangioleiomyomatosis (LAM) is remarkable. In the year 2000, TSC2 gene mutations were found in LAM cells; in 2001 the tuberous sclerosis complex (TSC) genes were discovered to regulate cell size in Drosophila via the kinase TOR (target of rapamycin); and in 2008 the result...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Thoracic Society
2010
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137149/ https://ncbi.nlm.nih.gov/pubmed/20160148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200909-104JS |
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