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Mammalian Target of Rapamycin Signaling and Autophagy: Roles in Lymphangioleiomyomatosis Therapy

The pace of progress in lymphangioleiomyomatosis (LAM) is remarkable. In the year 2000, TSC2 gene mutations were found in LAM cells; in 2001 the tuberous sclerosis complex (TSC) genes were discovered to regulate cell size in Drosophila via the kinase TOR (target of rapamycin); and in 2008 the result...

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書誌詳細
主要な著者: Yu, Jane, Parkhitko, Andrey A., Henske, Elizabeth Petri
フォーマット: Artigo
言語:Inglês
出版事項: American Thoracic Society 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137149/
https://ncbi.nlm.nih.gov/pubmed/20160148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200909-104JS
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