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Role of mammalian target of rapamycin signaling in autophagy and the neurodegenerative process using a senescence accelerated mouse-prone 8 model

The mammalian target of rapamycin (mTOR) kinase is an inhibitor of autophagy, which is an intracellular system involved in the degradation of long-lived proteins and organelles in lysosomes. Recent evidence suggests that the steady incline in mTOR function during aging may be associated with the cog...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Wang, Yanyong, Ma, Qinying, Ma, Xiaowei, Zhang, Zhongxia, Liu, Na, Wang, Mingwei
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5526151/
https://ncbi.nlm.nih.gov/pubmed/28810557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4618
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