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Aberrant Epigenetic and Genetic Marks Are Seen in Myelodysplastic Leukocytes and Reveal Dock4 as a Candidate Pathogenic Gene on Chromosome 7q

Myelodysplastic syndromes (MDS) are characterized by abnormal and dysplastic maturation of all blood lineages. Even though epigenetic alterations have been seen in MDS marrow progenitors, very little is known about the molecular alterations in dysplastic peripheral blood cells. We analyzed the methy...

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Detalhes bibliográficos
Main Authors: Zhou, Li, Opalinska, Joanna, Sohal, Davendra, Yu, Yiting, Mo, Yongkai, Bhagat, Tushar, Abdel-Wahab, Omar, Fazzari, Melissa, Figueroa, Maria, Alencar, Cristina, Zhang, Jinghang, Kambhampati, Suman, Parmar, Simrit, Nischal, Sangeeta, Hueck, Christoph, Suzuki, Masako, Freidman, Ellen, Pellagatti, Andrea, Boultwood, Jacqueline, Steidl, Ulrich, Sauthararajah, Yogen, Yajnik, Vijay, Mcmahon, Christine, Gore, Steven D., Platanias, Leonidas C., Levine, Ross, Melnick, Ari, Wickrema, Amittha, Greally, John M., Verma, Amit
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137092/
https://ncbi.nlm.nih.gov/pubmed/21532034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.235028
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