Inhibition of the TGF-β receptor I kinase promotes hematopoiesis in MDS

MDS is characterized by ineffective hematopoiesis that leads to peripheral cytopenias. Development of effective treatments has been impeded by limited insight into pathogenic pathways governing dysplastic growth of hematopoietic progenitors. We demonstrate that smad2, a downstream mediator of transf...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhou, Li, Nguyen, Aaron N., Sohal, Davendra, Ying Ma, Jing, Pahanish, Perry, Gundabolu, Krishna, Hayman, Josh, Chubak, Adam, Mo, Yongkai, Bhagat, Tushar D., Das, Bhaskar, Kapoun, Ann M., Navas, Tony A., Parmar, Simrit, Kambhampati, Suman, Pellagatti, Andrea, Braunchweig, Ira, Zhang, Ying, Wickrema, Amittha, Medicherla, Satyanarayana, Boultwood, Jacqueline, Platanias, Leonidas C., Higgins, Linda S., List, Alan F., Bitzer, Markus, Verma, Amit
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2008
Subjects:
Neoplasia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2569182/
https://ncbi.nlm.nih.gov/pubmed/18474728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-139824
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items