ICP34.5 Protein of Herpes Simplex Virus Facilitates the Initiation of Protein Translation by Bridging Eukaryotic Initiation Factor 2α (eIF2α) and Protein Phosphatase 1

The ICP34.5 protein of herpes simplex virus type 1 is a neurovirulence factor that plays critical roles in viral replication and anti-host responses. One of its functions is to recruit protein phosphatase 1 (PP1) that leads to the dephosphorylation of the α subunit of translation initiation factor e...

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Main Authors: Li, Yapeng, Zhang, Cuizhu, Chen, Xiangdong, Yu, Jia, Wang, Yu, Yang, Yin, Du, Mingjuan, Jin, Huali, Ma, Yijie, He, Bin, Cao, Youjia
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Protein Synthesis and Degradation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137054/
https://ncbi.nlm.nih.gov/pubmed/21622569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.232439
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