Tissue-specific Distribution and Dynamic Changes of 5-Hydroxymethylcytosine in Mammalian Genomes

Cytosine residues in the vertebrate genome are enzymatically modified to 5-methylcytosine, which participates in transcriptional repression of genes during development and disease progression. 5-Methylcytosine can be further enzymatically modified to 5-hydroxymethylcytosine by the TET family of meth...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kinney, Shannon Morey, Chin, Hang Gyeong, Vaisvila, Romualdas, Bitinaite, Jurate, Zheng, Yu, Estève, Pierre-Olivier, Feng, Suhua, Stroud, Hume, Jacobsen, Steven E., Pradhan, Sriharsa
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137044/
https://ncbi.nlm.nih.gov/pubmed/21610077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.217083
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