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Comparison of a PreQ(1) Riboswitch Aptamer in Metabolite-bound and Free States with Implications for Gene Regulation

Riboswitches are RNA regulatory elements that govern gene expression by recognition of small molecule ligands via a high affinity aptamer domain. Molecular recognition can lead to active or attenuated gene expression states by controlling accessibility to mRNA signals necessary for transcription or...

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Main Authors: Jenkins, Jermaine L., Krucinska, Jolanta, McCarty, Reid M., Bandarian, Vahe, Wedekind, Joseph E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
RNA
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137038/
https://ncbi.nlm.nih.gov/pubmed/21592962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.230375
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