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Impaired Infectivity of Ritonavir-resistant HIV Is Rescued by Heat Shock Protein 90AB1

Certain ritonavir resistance mutations impair HIV infectivity through incomplete Gag processing by the mutant viral protease. Analysis of the mutant virus phenotype indicates that accumulation of capsid-spacer peptide 1 precursor protein in virus particles impairs HIV infectivity and that the protea...

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Detalhes bibliográficos
Main Authors: Joshi, Pheroze, Stoddart, Cheryl A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137033/
https://ncbi.nlm.nih.gov/pubmed/21602280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.248021
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