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Differential Effects of Murine and Human Factor X on Adenovirus Transduction via Cell-surface Heparan Sulfate

Serum coagulation factor X (FX) is proposed to play a major role in adenovirus tropism, promoting transduction by bridging the virus to cell-surface heparan sulfate proteoglycans (HSPGs). Both murine FX and human FX increased transduction by Ad.CMVfLuc, an adenovirus vector, in murine hepatocyte-lik...

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Hlavní autoři: Zaiss, Anne K., Lawrence, Roger, Elashoff, David, Esko, Jeffrey D., Herschman, Harvey R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137028/
https://ncbi.nlm.nih.gov/pubmed/21596747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241562
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