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Differential Effects of Murine and Human Factor X on Adenovirus Transduction via Cell-surface Heparan Sulfate
Serum coagulation factor X (FX) is proposed to play a major role in adenovirus tropism, promoting transduction by bridging the virus to cell-surface heparan sulfate proteoglycans (HSPGs). Both murine FX and human FX increased transduction by Ad.CMVfLuc, an adenovirus vector, in murine hepatocyte-lik...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137028/ https://ncbi.nlm.nih.gov/pubmed/21596747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.241562 |
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