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Cell Surface Heparan Sulfate Promotes Replication of Toxoplasma gondii

Previous work suggests that cell surface heparan sulfate acts as a receptor for the Apicomplexan parasite Toxoplasma gondii. Using Chinese hamster ovary cell mutants defective in heparan sulfate biosynthesis, we show that heparan sulfate is necessary and sufficient for infectivity. Further, we demon...

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Detalhes bibliográficos
Main Authors: Bishop, Joseph R., Crawford, Brett E., Esko, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1231081/
https://ncbi.nlm.nih.gov/pubmed/16113255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.9.5395-5401.2005
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