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Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis
Aldo-keto reductase 1B7 (AKR1B7) is proposed to play a role in detoxification of by-products of lipid peroxidation. In this article, we show that activation of the nuclear receptor farnesoid X receptor (FXR) induces AKR1B7 expression in the liver and intestine, and reduces the levels of malondialdeh...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The American Society for Biochemistry and Molecular Biology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137022/ https://ncbi.nlm.nih.gov/pubmed/21642744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M015859 |
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