Aldo-keto reductase 1B7 is a target gene of FXR and regulates lipid and glucose homeostasis

Aldo-keto reductase 1B7 (AKR1B7) is proposed to play a role in detoxification of by-products of lipid peroxidation. In this article, we show that activation of the nuclear receptor farnesoid X receptor (FXR) induces AKR1B7 expression in the liver and intestine, and reduces the levels of malondialdeh...

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Bibliografiske detaljer
Main Authors: Ge, Xuemei, Yin, Liya, Ma, Huiyan, Li, Tiangang, Chiang, John Y. L., Zhang, Yanqiao
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2011
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137022/
https://ncbi.nlm.nih.gov/pubmed/21642744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M015859
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