Proteostasis Strategies for Restoring α(1)-Antitrypsin Deficiency

The function of the human proteome is defined by the proteostasis network (PN) (Science 2008;319:916; Science 2010;329:766), a biological system that generates, protects, and, where necessary, degrades a protein to optimize the cell, tissue, and organismal response to diet, stress, and aging. Numero...

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Bibliographic Details
Main Authors: Bouchecareilh, Marion, Conkright, Juliana J., Balch, William E.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2010
Subjects:
Twenty-Fifth Transatlantic Airway Conference: Protein Misfolding and Obstructive Lung Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136960/
https://ncbi.nlm.nih.gov/pubmed/21030523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.201001-016AW
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