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Sequestering Rac with PKA confers cAMP control of cytoskeletal remodeling

Rac GTPases promote formation of membrane ruffles, yet how key effectors of this small GTPase operate in response to intracellular signals is not well established. In our recent report, “Anchored PKA recruitment of active Rac,” we identify a cortical actin cytoskeletal signaling complex containing a...

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Autori principali: Logue, Jeremy S, Whiting, Jennifer L, Scott, John D
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136949/
https://ncbi.nlm.nih.gov/pubmed/21776420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/sgtp.2.3.16487
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