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A role of IL-1R1 signaling in the differentiation of Th17 cells and the development of autoimmune diseases

IL-1 cytokine family plays a key role in the innate immune response against pathogen- and danger-associated molecular patterns. More recently, IL-1 receptor type 1 (IL-R1) signaling has been identified as a critical step in the differentiation and commitment of Th17 cells, which mediate the developm...

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Autori principali: Sha, Yonggang, Markovic-Plese, Silva
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136902/
https://ncbi.nlm.nih.gov/pubmed/21776333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/self.2.1.15639
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