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Repair of the Major Lesion Resulting from C5′-Oxidation of DNA

Oxidation of the C5′-position of DNA results in direct strand scission. The 3′-fragments produced contain DNA lesions at their 5′-termini. The major DNA lesion contains an aldehyde at its C5′-position but its nucleobase is unmodified. Excision of the lesion formed from oxidation of thymidine (T-al)...

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Bibliografski detalji
Glavni autori: Jung, Kwan-Young, Kodama, Tetsuya, Greenberg, Marc M.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136800/
https://ncbi.nlm.nih.gov/pubmed/21696131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200787e
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