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Repair of the Major Lesion Resulting from C5′-Oxidation of DNA
Oxidation of the C5′-position of DNA results in direct strand scission. The 3′-fragments produced contain DNA lesions at their 5′-termini. The major DNA lesion contains an aldehyde at its C5′-position but its nucleobase is unmodified. Excision of the lesion formed from oxidation of thymidine (T-al)...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136800/ https://ncbi.nlm.nih.gov/pubmed/21696131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200787e |
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