Adenylate cyclase toxin is critical for colonization and pertussis toxin is critical for lethal infection by Bordetella pertussis in infant mice.

Proliferation of Bordetella pertussis in the lungs of infant mice challenged by the intranasal route was examined. The bacteria rapidly proliferated in the lungs of mice challenged with a sublethal dose of a wild-type strain (BP338) or a filamentous hemagglutinin mutant (BPM409) from 500 at day 0 to...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Goodwin, M S, Weiss, A A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1990
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC313675/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2401570/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.58.10.3445-3447.1990
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