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Suppression of Platelet Aggregation by Bordetella pertussis Adenylate Cyclase Toxin

The effect of Bordetella pertussis adenylate cyclase toxin (ACT) on platelet aggregation was investigated. This cell-invasive adenylate cyclase completely suppressed ADP (10 μM)-induced aggregation of rabbit platelets at 3 μg/ml and strongly suppressed thrombin (0.2 U/ml)-induced aggregation at 10 μ...

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Detalhes bibliográficos
Main Authors: Iwaki, Masaaki, Kamachi, Kazunari, Heveker, Nikolaus, Konda, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC96579/
https://ncbi.nlm.nih.gov/pubmed/10338478
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