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Suppression of Platelet Aggregation by Bordetella pertussis Adenylate Cyclase Toxin

The effect of Bordetella pertussis adenylate cyclase toxin (ACT) on platelet aggregation was investigated. This cell-invasive adenylate cyclase completely suppressed ADP (10 μM)-induced aggregation of rabbit platelets at 3 μg/ml and strongly suppressed thrombin (0.2 U/ml)-induced aggregation at 10 μ...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Iwaki, Masaaki, Kamachi, Kazunari, Heveker, Nikolaus, Konda, Toshifumi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC96579/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10338478/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.67.6.2763-2768.1999
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