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HEXIM1 is a critical determinant of the response to tamoxifen
Tamoxifen resistance is a major problem in the treatment of Estrogen Receptor (ER) positive patients. We have previously reported that Hexamethylene bis-acetamide Inducible Protein 1 (HEXIM1) inhibits ERα activity by competing with ERα for binding to cyclin T1, a subunit of Positive Transcription El...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136650/ https://ncbi.nlm.nih.gov/pubmed/21423213 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.76 |
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