Antimalarial Activity of Potential Inhibitors of Plasmodium falciparum Lactate Dehydrogenase Enzyme Selected by Docking Studies

The Plasmodium falciparum lactate dehydrogenase enzyme (PfLDH) has been considered as a potential molecular target for antimalarials due to this parasite's dependence on glycolysis for energy production. Because the LDH enzymes found in P. vivax, P. malariae and P. ovale (pLDH) all exhibit ∼90%...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Penna-Coutinho, Julia, Cortopassi, Wilian Augusto, Oliveira, Aline Alves, França, Tanos Celmar Costa, Krettli, Antoniana Ursine
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136448/
https://ncbi.nlm.nih.gov/pubmed/21779323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021237
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky