Proteins in the Nutrient-Sensing and DNA Damage Checkpoint Pathways Cooperate to Restrain Mitotic Progression following DNA Damage

Checkpoint pathways regulate genomic integrity in part by blocking anaphase until all chromosomes have been completely replicated, repaired, and correctly aligned on the spindle. In Saccharomyces cerevisiae, DNA damage and mono-oriented or unattached kinetochores trigger checkpoint pathways that bif...

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Bibliographic Details
Main Authors: Searle, Jennifer S., Wood, Matthew D., Kaur, Mandeep, Tobin, David V., Sanchez, Yolanda
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136438/
https://ncbi.nlm.nih.gov/pubmed/21779180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002176
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