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Working hard for recovery: mitotic kinases in the DNA damage checkpoint

Cell division in mitosis is tightly regulated via a group of protein kinases. Activation of these mitotic kinases is inhibited by the DNA damage checkpoint that arrests the cell cycle in interphase and prevents mitotic entry. Interestingly, it has been shown that the DNA damage checkpoint is feedbac...

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Bibliographic Details
Main Author: Peng, Aimin
Format: Artigo
Language:Inglês
Published: BioMed Central 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3641994/
https://ncbi.nlm.nih.gov/pubmed/23618492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3701-3-20
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