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A Dimension Reduction Approach for Modeling Multi-Locus Interaction in Case-Control Studies

Studying one locus or one single nucleotide polymorphism (SNP) at a time may not be sufficient to understand complex diseases because they are unlikely to result from the effect of only one SNP. Each SNP alone may have little or no effect on the risk of the disease, but together they may increase th...

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Bibliographic Details
Main Authors: Basu, Saonli, Pan, Wei, Oetting, William S.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136376/
https://ncbi.nlm.nih.gov/pubmed/21734407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000328842
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