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A Dimension Reduction Approach for Modeling Multi-Locus Interaction in Case-Control Studies

Studying one locus or one single nucleotide polymorphism (SNP) at a time may not be sufficient to understand complex diseases because they are unlikely to result from the effect of only one SNP. Each SNP alone may have little or no effect on the risk of the disease, but together they may increase th...

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Detalhes bibliográficos
Main Authors: Basu, Saonli, Pan, Wei, Oetting, William S.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136376/
https://ncbi.nlm.nih.gov/pubmed/21734407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000328842
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