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Two-Stage Design of Sequencing Studies for Testing Association with Rare Variants
Multiple rare variants have been suggested as accounting for some of the associations with common single nucleotide polymorphisms identified in genome-wide association studies or possibly some of the as yet undiscovered heritability. We consider the power of various approaches to designing substudie...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
S. Karger AG
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136374/ https://ncbi.nlm.nih.gov/pubmed/21734405 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000328193 |
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