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Major source of antigenic peptides for the MHC class I pathway is produced during the pioneer round of mRNA translation
The MHC class I antigen presentation pathway allows the immune system to distinguish between self and nonself. Despite extensive research on the processing of antigenic peptides, little is known about their origin. Here, we show that mRNAs carrying premature stop codons that prevent the production o...
Tallennettuna:
| Päätekijät: | , , , , , , |
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| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3136330/ https://ncbi.nlm.nih.gov/pubmed/21709220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104104108 |
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