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Translation of pre-spliced RNAs in the nuclear compartment generates peptides for the MHC class I pathway

The scanning of maturing mRNAs by ribosomes plays a key role in the mRNA quality control process. When ribosomes first engage with the newly synthesized mRNA, and if peptides are produced, is unclear, however. Here we show that ribosomal scanning of prespliced mRNAs occurs in the nuclear compartment...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Apcher, Sébastien, Millot, Guy, Daskalogianni, Chrysoula, Scherl, Alexander, Manoury, Bénédicte, Fåhraeus, Robin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816435/
https://ncbi.nlm.nih.gov/pubmed/24082107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309956110
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