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Translation of pre-spliced RNAs in the nuclear compartment generates peptides for the MHC class I pathway
The scanning of maturing mRNAs by ribosomes plays a key role in the mRNA quality control process. When ribosomes first engage with the newly synthesized mRNA, and if peptides are produced, is unclear, however. Here we show that ribosomal scanning of prespliced mRNAs occurs in the nuclear compartment...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816435/ https://ncbi.nlm.nih.gov/pubmed/24082107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309956110 |
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