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Translation of pre-spliced RNAs in the nuclear compartment generates peptides for the MHC class I pathway
The scanning of maturing mRNAs by ribosomes plays a key role in the mRNA quality control process. When ribosomes first engage with the newly synthesized mRNA, and if peptides are produced, is unclear, however. Here we show that ribosomal scanning of prespliced mRNAs occurs in the nuclear compartment...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3816435/ https://ncbi.nlm.nih.gov/pubmed/24082107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309956110 |
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