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Translation of pre-spliced RNAs in the nuclear compartment generates peptides for the MHC class I pathway

The scanning of maturing mRNAs by ribosomes plays a key role in the mRNA quality control process. When ribosomes first engage with the newly synthesized mRNA, and if peptides are produced, is unclear, however. Here we show that ribosomal scanning of prespliced mRNAs occurs in the nuclear compartment...

詳細記述

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書誌詳細
主要な著者: Apcher, Sébastien, Millot, Guy, Daskalogianni, Chrysoula, Scherl, Alexander, Manoury, Bénédicte, Fåhraeus, Robin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816435/
https://ncbi.nlm.nih.gov/pubmed/24082107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309956110
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