Artemisinin activity against Plasmodium falciparum requires hemoglobin uptake and digestion

Combination regimens that include artemisinin derivatives are recommended as first line antimalarials in most countries where malaria is endemic. However, the mechanism of action of artemisinin is not fully understood and the usefulness of this drug class is threatened by reports of decreased parasi...

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Detaylı Bibliyografya
Asıl Yazarlar: Klonis, Nectarios, Crespo-Ortiz, Maria P., Bottova, Iveta, Abu-Bakar, Nurhidanatasha, Kenny, Shannon, Rosenthal, Philip J., Tilley, Leann
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2011
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3136263/
https://ncbi.nlm.nih.gov/pubmed/21709259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104063108
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