Llwytho...

Insulin receptor substrate chico acts with the transcription factor FOXO to extend Drosophila lifespan

Although extensively studied in C. elegans, no work has yet demonstrated for Drosophila melanogaster whether reduced insulin/IGF signaling (IIS) requires the FOXO transcription factor (foxo) to extend lifespan. Here we conduct genetic epistasis analysis to determine if foxo is required for chico mut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yamamoto, Rochele, Tatar, Marc
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135774/
https://ncbi.nlm.nih.gov/pubmed/21518241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00716.x
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