The insulin receptor substrate Chico regulates antibacterial immune function in Drosophila

BACKGROUND: Molecular and genetic studies in model organisms have recently revealed a dynamic interplay between immunity and ageing mechanisms. In the fruit fly Drosophila melanogaster, inhibition of the insulin/insulin-like growth factor signaling pathway prolongs lifespan, and mutations in the ins...

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Bibliografiske detaljer
Udgivet i:Immun Ageing
Main Authors: McCormack, Sarah, Yadav, Shruti, Shokal, Upasana, Kenney, Eric, Cooper, Dustin, Eleftherianos, Ioannis
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4852101/
https://ncbi.nlm.nih.gov/pubmed/27134635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-016-0072-1
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